farin peony tsantsa

Sunan samfur:Farin Cire Peonyfoda

Wani Suna:Farin Blossom na Kasar Sin yana Cire Foda

Tushen Botanical:Radix Paeoniae Alba

Sinadaran:Jimlar glucosides na Paeonia (TGP):Paeoniflorin, Oxypaeoniflorin, Albiflorin, Benzoylpaeoniflorin

Ƙayyadaddun bayanai:Paeoniflorin10% ~ 40% (HPLC), 1.5%Albasides, 80%Glycosides

Lambar CAS:23180-57-6

Launi: Yellowish-kasa-kasafodatare da halayyar wari da dandano

GMOMatsayi: GMO Kyauta

Shiryawa: a cikin 25kgs fiber ganguna

Adana: Ajiye akwati a buɗe a wuri mai sanyi, busasshiyar wuri, Nisantar haske mai ƙarfi

Rayuwar Shelf: watanni 24 daga ranar samarwa

Farin Cire Peonyyana nufin fitar da sinadarai masu aiki daga farin peony ta hanyar kimiyya bisa ga wata fasaha ta musamman.A bisa nazarin masana, sinadaran da ake amfani da su na tsantsar farin peony ga jikin dan Adam sune kamar haka Chart.Hudu daga cikin mafi mahimmanci sune Paeoniflorin, Oxypaeoniflorin, Albiflorin, da Benzoylpaeoniflorin.

Ana fitar da tsantsar farin peony daga busasshiyar tushen Paeonia lactiflora Pall., tsiro na dangin Ranunculaceae.Babban bangarensa shine paeoniflorin, wanda za'a iya amfani dashi sosai ba kawai a fannin likitanci ba har ma a cikin masana'antar kayan kwalliya.Tsantsar farin peony shine mai hana ayyukan PDE4 mai inganci sosai.Ta hanyar hana ayyukan PDE4, zai iya yin cAMP na nau'o'in ƙwayoyin cuta da ƙwayoyin cuta (irin su neutrophils, macrophages, T lymphocytes da eosinophils, da dai sauransu) ya kai ga maida hankali wanda ya isa ya hana kunna ƙwayoyin ƙwayoyin ƙwayoyin cuta da kuma haifar da sakamako mai kumburi.Har ila yau yana da analgesic, antispasmodic, anti-ulcer, vasodilator, ƙara yawan jini na gabobin jiki, antibacterial, hanta-kare, detoxifying, anti-mutagenic, da anti-tumo effects.

1,2,3,6-tetragalloyl glucose, 1,2,3,4,6-pentagalloyl glucose da kuma daidai hexagalloyl glucose da heptagalloyl glucose an ware daga tannin na farin peony tushen.Har ila yau, ya ƙunshi catechin dextrorotatory da mai maras tabbas.Mai maras tabbas ya ƙunshi benzoic acid, peony phenol da sauran barasa da phenols.1. Paeoniflorin: dabarar kwayoyin C23H28O11, nauyin kwayoyin halitta 480.45.Hygroscopic amorphous foda, [α] D16-12.8 ° (C=4.6, methanol), tetraacetate shine lu'ulu'u na allura mara launi, mp.196 ℃.2. Paeonol: Synonyms sune paeonol, peony barasa, paeonal, da peonol.Tsarin kwayoyin halitta C9H10O3, nauyin kwayoyin halitta 166.7.Lu'ulu'u marasa launi na allura (ethanol), mp.50 ℃, dan kadan mai narkewa a cikin ruwa, na iya canzawa tare da tururin ruwa, mai narkewa a cikin ethanol, ether, acetone, chloroform, benzene da carbon disulfide.3. Wasu: Ya ƙunshi ƙaramin adadin oxypaeoniflorin, albiforin, benzoylpaeoniflorin, lactiflorin, sabon monoterpene paeoniflorigenone tare da tasirin hana neuromuscular akan mice, 1,2,3,4,6-Pentagalloylglucose tare da tasirin antiviral, gallotannin, gallic-d acid, ethyl gallate, tannin, β-sitosterol, sugar, sitaci, gamsai, da dai sauransu.

Ayyuka:

1. Anti-mai kumburi, antibacterial da antiviral sakamako.Farin peony tsantsa yana da tasiri mai mahimmanci na hanawa akan kwai fari m kumburi mai kumburi a cikin berayen kuma yana hana yaduwar granuloma auduga.Jimlar glycosides na paeony suna da anti-mai kumburi da tasirin immunomodulatory mai dogaro da jiki akan berayen da ke da amosanin gabbai.Shirye-shiryen fararen peony suna da wasu tasirin hanawa akan Staphylococcus aureus, hemolytic Streptococcus, pneumococcus, Shigella dysenteriae, Typhoid bacillus, Vibrio cholerae, Escherichia coli da Pseudomonas aeruginosa.Bugu da ƙari, 1:40 decoction na peony zai iya hana Jingke 68-1 cutar da cutar ta herpes.
2. Hepatoprotective sakamako.Farin peony tsantsa yana da tasiri mai mahimmanci akan lalacewar hanta da haɓakar SGPT da D-galactosamine ya haifar.Yana iya rage SGPT da mayar da hanta cell raunuka da necrosis zuwa al'ada.Tushen ethanol na tushen peony fari zai iya rage haɓakar jimlar ayyukan lactate dehydrogenase da isoenzymes a cikin berayen tare da mummunan rauni na hanta wanda aflatoxin ya haifar.Jimlar glycosides na paeony na iya hana haɓakar SGPT da lactate dehydrogenase a cikin berayen da ke haifar da carbon tetrachloride, kuma suna da tasirin antagonistic akan eosinophilic degeneration da necrosis na hanta nama.
3. Tasirin Antioxidant: Farin Tushen Tushen Peony TGP yana da tasirin maganin antioxidant da tantanin halitta, kuma yana iya samun sakamako mai lalacewa akan radicals kyauta.
4. Tasirin tsarin zuciya da jijiyoyin jini tsantsa Farin peony na iya faɗaɗa tasoshin jini na keɓaɓɓen zuciya, tsayayya da matsanancin ischemia na myocardial a cikin berayen da pituitaryin ke haifar da shi, da rage juriya na jijiyoyin bugun jini da haɓaka kwararar jini yayin allura a cikin jijiya.Paeoniflorin kuma yana da tasirin dilating akan tasoshin jini na jijiyoyin jini da tasoshin jini, kuma yana haifar da raguwar hawan jini.Nazarin ya nuna cewa paeoniflorin, wani tsantsa daga tushen farin peony, yana da tasiri mai hanawa akan ADP-induced tarin platelet a cikin berayen in vitro.
5. Abubuwan da ke faruwa na gastrointestinal fili Farin peony tsantsa yana da tasiri mai hanawa a kan ƙayyadaddun ƙayyadaddun hanzari na intestinal hyperexcitability na hanji da kuma raguwa da barium chloride ya haifar, amma ba shi da wani tasiri akan raguwa da acetylcholine ya haifar.Ruwan da aka fitar da ruwa na licorice da farin tushen peony (0.21g) yana da tasiri mai mahimmanci akan motsi na tsoka mai santsi na hanji a cikin zomaye a vivo.Haɗin tasirin biyu ya fi na ko dai shi kaɗai, kuma tasirin rage mitar ya fi ƙarfi fiye da tasirin rage girman girma.Rage raguwar ƙwayar hanji na zomo 20 zuwa 25 mintuna bayan gudanarwa shine 64.71% da 70.59% na abin da ke cikin ƙungiyar kulawa ta al'ada, bi da bi, kuma ya fi ƙarfin atropine (0.25 MG) a cikin ƙungiyar kulawa mai kyau.Paeoniflorin yana da tasirin hanawa akan keɓaɓɓen bututun hanji da kuma motsin ciki na ciki a cikin aladu da berayen, da kuma ƙwayar bera mai santsi mai santsi, kuma yana iya haifar da ƙazantawa da oxytocin ke haifar.Yana da tasirin daidaitawa tare da tsantsar barasa na Chemicalbook FM100 na licorice.Paeoniflorin yana da tasiri mai mahimmanci na hanawa akan gyambon ciki a cikin berayen da ke haifar da damuwa.
6. Sedative, analgesic, da anticonvulsant effects.Farar alluran peony da paeoniflorin duka suna da tasirin kwantar da hankali da analgesic.Allurar da ɗan ƙaramin paeoniflorin a cikin ventricles na kwakwalwa na dabbobi na iya haifar da yanayin barci a fili.Intraperitoneal allura na 1g/kg na paeoniflorin daga farin peony tushen tsantsa a cikin berayen iya rage da dabbobi 'spontaneous ayyukan, tsawaita lokacin barci na pentobarbital, hana writhing dauki na berayen lalacewa ta hanyar intraperitoneal allurar acetic acid, da kuma tsayayya pentylenettrazole.Ya haifar da tashin hankali.Jimlar glycosides na paeony suna da tasirin analgesic masu mahimmanci kuma suna iya haɓaka tasirin analgesic na morphine da clonidine.Naloxone baya shafar tasirin analgesic na jimlar glycosides na paeony, yana ba da shawarar cewa ka'idar analgesic ɗinta ba ta motsa masu karɓar opioid ba.Cire Peony na iya hana rikicewar da strychnine ke haifarwa.Paeoniflorin ba shi da wani tasiri a kan keɓaɓɓen tsokar kwarangwal, don haka ana tunanin cewa tasirin anticonvulsant yana tsakiyar.
7. Tasiri akan tsarin jini: Cire barasa na Paeony na iya hana haɗuwar platelet a cikin zomaye waɗanda ADP, collagen, da arachidonic acid a cikin vitro suka jawo.
8. Tasiri akan tsarin rigakafi.Tushen farin peony na iya haɓaka samar da ƙwayoyin rigakafin ƙwayoyin cuta da kuma haɓaka amsawar ɓacin rai na ɓeraye ga tumaki jajayen ƙwayoyin jini.Farin peony decoction na iya adawa da tasirin hanawa na cyclophosphamide akan na gefen jini T lymphocytes a cikin mice, mayar da su zuwa matakan al'ada, da mayar da ƙarancin aikin rigakafi na salula zuwa al'ada.Jimlar glycosides na paeony na iya haɓaka haɓakar ƙwayoyin lymphocytes na splenic a cikin berayen da concanavalin ya jawo, haɓaka samar da α-interferon a cikin leukocytes na jini na igiyar mutum wanda cutar cutar kajin Newcastle ta haifar da cutar kajin kaji, kuma suna da tasirin bidirectional akan samar da interleukin-2 a cikin bera. splenocytes ta hanyar concanavalin.daidaita tasiri.
9. Tasirin Ƙarfafawa: Farin ruwan barasa na peony na iya tsawaita lokacin yin iyo na ɓeraye da lokacin rayuwa mai daɗi na beraye, kuma yana da wani tasiri mai ƙarfi.
10. Anti-mutagenic da anti-tumo effects Farin peony tsantsa zai iya tsoma baki tare da aikin enzyme na cakuda S9, kuma zai iya hana metabolites na benzopyrene kuma ya hana tasirin mutagenic.

11. Sauran illolin (1) Tasirin Antipyretic: Paeoniflorin yana da tasirin antipyretic akan beraye tare da zazzabin wucin gadi kuma yana iya rage yawan zafin jikin berayen.(2) Tasirin haɓaka ƙwaƙwalwar ajiya: Jimlar glycosides na paeony na iya haɓaka ƙarancin koyo da samun ƙwaƙwalwar ajiya a cikin berayen da scopolamine ya haifar.(3) Tasirin anti-hypoxic: Jimlar glycosides na farin paeony na iya tsawaita lokacin rayuwa na beraye a ƙarƙashin matsa lamba na al'ada da hypoxia, rage yawan amfani da iskar oxygen na mice, da rage yawan mace-macen mice saboda guba na cyanide potassium da hypoxia.