Cirewar Iri ta Seleri 98% Apigenin

Sunan Samfurin:Cirewar ganyen seleriApigenin 98%

Sunan Latin: Apium graveolens L.

Lambar CAS:520-36-5

Sashen Shuka da Aka Yi Amfani da shi: Ganye

Sinadarin:Apigenin

Gwaji:Apigenin98.0% ta hanyar HPLC

Launi: Foda mai launin ruwan kasa zuwa rawaya tare da ƙamshi da ɗanɗano na musamman

Matsayin GMO: Babu GMO

Shiryawa: a cikin ganga na fiber 25kgs

Ajiya: A ajiye akwati a wuri mai sanyi da bushewa, a ajiye shi nesa da haske mai ƙarfi

Rayuwar Shiryayye: Watanni 24 daga ranar samarwa

Cirewar Iri ta Seleri 98% Apigenin: Kariyar Halitta Mai Kyau Don Lafiya Mai Kyau

Bayanin Samfuri
Cirewar Iri ta Seleri 98% Apigeninsinadari ne na halitta mai tsafta wanda aka samo daga tsabanApium graveolens, wanda aka daidaita don samar da kashi 98% na apigenin - wani flavonoid mai ƙarfi wanda aka san shi da fa'idodin kiwon lafiya da yawa. Ana samar da wannan ruwan ta hanyar ci gaba da fitar da ethanol da hanyoyin sarrafawa masu inganci, yana tabbatar da ingantaccen ƙarfi da aminci. Ya dace da amfani da abinci mai gina jiki, abinci mai aiki, da magunguna, yana haɗa hikimar ganye ta gargajiya tare da ingantaccen kimiyya na zamani.

Muhimman Fa'idodin Lafiya

1. Tallafin Zuciya da Jijiyoyin Jiki
   • Yana Rage Hawan Jini da Cholesterol: Ya ƙunshi phthalides (misali, 3-n-butylphthalide) da flavonoids waɗanda ke sassauta jijiyoyin jini, rage matakan lipid (TC, LDL-C, TG), da kuma inganta zagayawar jini, wanda ke tallafawa lafiyar zuciya.
   • Tasirin Hawan Jini: An nuna shi a gwaje-gwajen asibiti don haɓaka kwararar jini da kuma daidaita kwararar calcium/potassium a cikin ƙwayoyin jijiyoyin jini, yana rage haɗarin hauhawar jini.
2. Kayayyakin hana kumburi da hana tsufa
   • Yana yaƙi da kumburi mai ɗorewa wanda ke da alaƙa da amosanin gabbai, matsalolin hanta, da cututtukan zuciya da jijiyoyin jini ta hanyar amfani da flavonoids (apigenin, quercetin) da polysaccharides.
   • Yana rage tsattsauran ra'ayi tare da phenolic acid (caffeic acid, ferulic acid), yana kare shi daga damuwa ta oxidative da lalacewar ƙwayoyin halitta.
3. Taimakon Kariya da Narkewa daga Ciwon Hanta
   • Yana rage tarin kitsen hanta, yana inganta aikin enzymes, kuma yana inganta tsarkakewa ta hanyar inganta kwararar bile.
   • Yana aiki a matsayin maganin diuretic, yana rage kumburi, kuma yana tallafawa lafiyar hanji ta hanyar daidaita majina na ciki da rage samuwar gyambon ciki.
4. Rigakafin Ciwon daji da Tallafin Garkuwar Jiki
   • Apigenin yana hana ci gaban ƙari ta hanyar daidaita ayyukan hormones, toshe yaduwar ƙwayoyin cuta masu canza halitta, da kuma kare mutuncin DNA.
   • Polyacetylenes da ƙwayoyin cuta masu kashe ƙwayoyin cuta suna yaƙi da cututtukan ƙwayoyin cuta (misali, UTIs) kuma suna ƙarfafa garkuwar jiki.
5. Ingantaccen Tsarin Jiki da Fahimta
   • Yana haɓaka aikin mitochondrial, yana taimakawa wajen sarrafa nauyi, kuma yana haɓaka aikin motsa jiki ta hanyar inganta metabolism na lipid.
   • Yana tallafawa kare lafiyar jijiyoyi da kuma fahimtar kwakwalwa ta hanyar rawar da apigenin ke takawa wajen ƙarfafa tsarin jijiyoyi da kuma rage kumburin jijiyoyi.

Aikace-aikace

• Sinadaran Abinci Mai Gina Jiki: An ƙera shi a cikin capsules (500-1500 mg/rana) don lafiyar zuciya, hana tsufa, da kuma tallafawa garkuwar jiki.
• Abincin Aiki: Ana ƙara shi a cikin abubuwan sha, sandunan furotin, da kayan ciye-ciye don fa'idodin metabolism da antioxidant.
• Magunguna: Ana amfani da shi a cikin magungunan rage hawan jini, magungunan kare hanta, da magungunan rage ciwon daji.
• Kayan shafawa: An haɗa shi cikin kula da fata don hana kumburi da kuma tasirin haɗa collagen.
• Maganin Ƙamshi: Yana ƙara wa miya, miya, da kayayyakin nama kyau a matsayin madadin halitta ga ƙarin sinadarai na roba.

Bayanan Fasaha

• Sinadarin Aiki: Apigenin ≥98% (HPLC).
• Hanyar Cirewa: Ethanol-mai narkewar ruwa, an fesa shi da maltodextrin.
• Bayyanar: Foda mai laushi fari zuwa fari.
• Takaddun shaida: Ba GMO ba ne, ba shi da gluten, babu ƙari.

Me Yasa Zabi Mu?

• Keɓancewa: Ana samunsa a cikin foda mai yawa, capsules, ko ruwan da aka cire don yin lakabi na sirri.
• Isarwa Mai Sauri: Ana jigilar ta ta hanyar DHL/FedEx (kwanaki 5-10) ko jigilar kaya ta teku (kwanaki 15-45).
• Tabbatar da Inganci: An gwada wani ɓangare na uku don tsarki, ƙarfi, da ƙarfe masu nauyi.
• Samfuran Kyauta: An samar da samfuran g 5–10 don tabbatar da dakin gwaje-gwaje.

Tsaro & Amfani

• Yawan amfani: 500-1500 MG kowace rana, an daidaita shi don takamaiman magunguna.
• Gargaɗi: Yana iya yin mu'amala da magungunan da aka sarrafa ta hanyar CYP3A4 (misali, statins, magungunan hana ɗaukar ciki). Tuntuɓi mai ba da sabis na kiwon lafiya idan kuna da juna biyu ko kuna shan magani.

Tasirin hana ƙari

Apigenin yana taka muhimmiyar rawa wajen hana kamuwa da cutar kansa ta hanyar haifar da apoptosis a cikin layukan ƙwayoyin halitta daban-daban.

Ciwon daji na Ovarian:

An gano wasu bincike cewa apigenin na iya hana girma, yaduwa, da kuma canja wurin ca-ov3 (ƙwayar cutar kansar mahaifa ta ɗan adam); yana haifar da apoptosis na ca-ov3 ta hanyar kiyaye ƙwayoyin cutar kansa a cikin matakin G2/M. Tasirin yana da alaƙa da lokaci da kuma yawan amfani.

Ciwon daji na pancreas:

Apigenin na iya hana yaduwar ƙwayoyin cutar kansar pancreas. Apigenin yana sa ciwon ya yi tsanani ta hanyar rage tushen glucose, wanda shine abincin da ƙwayoyin cutar kansa ke rayuwa a kai. Bugu da ƙari, Apigenin na iya inganta ingancin maganin chemotherapy - gemcitabine.

Fahimtar Sinadaran Chemo

An gano cewa apigenin a cikin ƙarancin abun ciki yana da ƙarancin tasirin cytotoxic kuma ba zai iya haifar da ƙwayoyin cutar sankarar myeloid na ɗan adam (hl-60) zuwa apoptosis yadda ya kamata ba. Duk da haka, apigenin na iya haɓaka tasirin hana cisplatin (DDP) akan yaduwar ƙwayoyin hl-60 yayin da yake haɗuwa da yawan DDP daban-daban. Don haka Apigenin na iya samun tasirin kula da chemotherapy akan hl-60; Ƙarancin yawan apigenin kuma na iya rage juriyar ƙwayoyin hl-60 zuwa apoptosis da chemotherapy ke haifarwa, wanda ƙila yana da alaƙa da raguwar NF-κB da BCL-2. (NF-KB wani nau'in hadaddun furotin ne wanda ke sarrafa kwafi na DNA, samar da cytokines da rayuwar ƙwayoyin halitta; BCL-2 an ɓoye shi a cikin jiki ta hanyar kwayar halittar BCL2, shine ainihin memba na dangin sunadaran BCL-2 waɗanda zasu iya daidaita mutuwar ƙwayoyin halitta)

Kariyar hanta

Apigenin na iya rage raunin hanta da ischemia-reperfusion ke haifarwa ta hanyar hana lipid peroxidation da kuma kawar da free radicals.

Apigenin na iya rage raunin hanta da damuwa ta oxidative ke haifarwa saboda tasirinsa mai ƙarfi na antioxidant da anti-inflammatory.

Gwaje-gwajen magunguna sun tabbatar da cewa apigenin yana da tasiri mai kyau ga raunin hanta/hepatocyte da barasa ke haifarwa, kuma babban hanyarsa tana da alaƙa da hana bayyanar CYP2E1 a cikin hanta/hepatocyte.

Hana osteoporosis

Apigenin yana hana osteoblastogenesis, osteoclastogenesis, kuma yana hana asarar ƙashi.

Apigenin yana kare ƙashi ta hanyar rage asarar ƙashi a jiki.

Wasu bincike da suka shafi MC3T3-E1, wani layin ƙwayoyin halitta mai suna osteoblast precursor wanda aka samo daga Mus musculus (linzamin kwamfuta) calvaria, sun gano cewa apigenin na iya hana TNF-α, IFN-γ, sannan ya haifar da fitar da wasu cytokines da ke haɓaka samuwar osteoclast.

Apigenin ya kuma hana bambance ƙwayoyin adipose masu mahimmanci na 3T3-L1 zuwa cikin ƙwayoyin adipose masu ƙarfi, don haka yana hana bambancewa mai hana bambancewa wanda ke haifar da bambancin adipocyte-induced IL-6, MCP-1, samfurin lectin.

Apigenin yana hana bambance-bambancen osteoclasts daga layukan ƙwayoyin halitta na RAW264.7 sannan yana hana samuwar osteoclasts masu yawa. Hakanan yana iya haifar da apoptosis na osteoclast da kuma hana resorption na ƙashi.

Ayyukan hana kumburi da hana oxidant

Apigenin yana hana tsarin kumburi, yana ƙara matakan IL-10 kuma yana daidaita sigogin damuwa na oxidative

Apigenin yana hana cytokines masu hana kumburi kuma yana haifar da samar da cytokine masu hana kumburi.

Wasu wallafe-wallafe sun nuna cewa apigenin yana rage kumburin nama wanda damuwa ta oxidative ke haifarwa a cikin kyallen ta hanyar daidaita alamomin damuwa na oxidative daban-daban, interleukins, alamomin enzyme na jini, da kuma bayyanar wasu enzymes da dama masu alaƙa.

Tsarin endocrine

Apigenin na iya daidaita sukarin jini, magance rashin isasshen thyroid da kuma sarrafa sinadarin lipid peroxidation. An gano cewa apigenin na iya ƙara yawan insulin da thyroxine a cikin dabbobin da ke fama da ciwon suga, da kuma rage yawan sukarin jini da kuma aikin glucose-6-phosphorylase (G-6-Pase).

Apigenin ya sauya tasirin karuwar cholesterol a cikin jini, karuwar lipid peroxidation na hanta (LPO) da kuma rage ayyukan antioxidants kamar catalase (CAT) da superoxide dismutase (SOD) a cikin dabbobin da alloxan ya haifar.

A cikin dabbobin da ke da yawan sukari a jini, apigenin na iya rage yawan cholesterol a cikin jini da kuma sinadarin lipid peroxidation a hanta, da kuma ƙara yawan aikin antioxidants a cikin ƙwayoyin halitta.

Abubuwan da ke cikin apigenin na maganin

Apigenin yana da matuƙar muhimmanci a cikin 'yan shekarun nan, a matsayin mai taimakawa lafiya saboda ƙarancin gubar da ke cikinsa da kuma tasirinsa ga lafiyar ƙwayoyin cutar kansa na yau da kullun idan aka kwatanta da sauran flavonoids masu alaƙa da tsarinsa. Akwai shaidu da yawa na bincike da suka nuna cewa apigenin yana da babban ƙarfin warkarwa ga cututtuka da yawa.