Gishirin Disodium na Pyrroloquinoline Quinone (PQQ)

Sunan Samfura: Pyrroloquinoline Quinone Disodium Gishiri

Lambar CAS: 122628-50-6/ 72909-34-3

Nauyin kwayoyin halitta: 374.17/ 330.21

Tsarin Kwayoyin Halitta: C14H4N2Na2O8/ C14H6N2O8

Bayani: Gishirin Disodium PQQ 99%；Acid PQQ 99%

Bayyanar: Fulawa mai launin ja zuwa launin ruwan kasa mai launin ja.

Amfani: Ana amfani da shi sosai don ƙarin abinci da kuma nutraceuticals.

Ajiya: A adana a cikin yanayi mai annashuwa da bushewa, a guji rana kai tsaye.

Tushen abinci na Quinone na Pyrroloquinoline

PQQ yana wanzuwa a zahiri a yawancin abincin kayan lambu, 'ya'yan itatuwa, da kayan lambu (alama), kuma ana iya gano matakan PQQ masu yawa a cikin kayayyakin waken soya da aka dafa, kamar kiwifruit, lychee, wake kore, tofu, rapeseed, mustard, shayi kore (camellia), barkono kore, alayyafo, da sauransu.

G.Haug ya gano cewa shine na uku a cikin redox cofactor a cikin ƙwayoyin cuta bayan nicotinamide da flavin (kodayake ya ɗauka cewa naphthoquinone ne). Anthony da Zatman sun kuma gano redox cofactors da ba a san su ba a cikin ethanol dehydrogenase. A cikin 1979, Salisbury da abokan aikinsa da kuma Duine da abokan aikinsu sun cire wannan tushe na ƙarya daga methanol dehydrogenase na dinoflagellates kuma suka gano tsarin kwayoyin halittarsa. Adachi da abokan aikinsa sun gano cewa Acetobacter shima yana ɗauke da PQQ.

Tsarin aikin Pyrroloquinoline Quinone

Pyrroloquinoline quinone (PQQ) ƙaramin ƙwayar quinone ce, wadda ke da tasirin redox, tana iya rage oxidant (antioxidant); sannan ana dawo da ita cikin siffa mai aiki ta hanyar glutathione. Da alama tana da ƙarfi sosai saboda tana iya yin dubban zagayowar kafin ta lalace, kuma sabuwa ce saboda tana da alaƙa da tsarin furotin na ƙwayoyin halitta (wasu antioxidants, manyan carotenoids kamar beta-carotene da astaxanthin, suna cikin takamaiman wurare na ƙwayoyin halitta, inda suke taka rawa sosai a fannin antioxidant). Saboda kusanci, PQQ da alama tana taka rawa kusa da sunadarai kamar carotenoids akan membranes na ƙwayoyin halitta.

Waɗannan ayyukan redox na iya canza ayyukan furotin da hanyoyin watsa siginar. Duk da cewa akwai bincike mai kyau da yawa a cikin vitro (samfuran rayuwa a waje), wasu sakamako masu kyau na ƙarin PQQ galibi suna da alaƙa da canza wasu hanyoyin watsa siginar ko fa'idodin su ga mitochondria. (Yi ƙarin aiki kuma inganta inganci).

Yana da sinadarin coenzyme a cikin ƙwayoyin cuta (don haka ga ƙwayoyin cuta, kamar bitamin B ne), amma da alama bai shafi mutane ba. Tunda wannan bai shafi mutane ba, wani labarin da aka buga a cikin Nature, wata mujallar kimiyya ta 2003, ya yi jayayya cewa ra'ayin cewa PQ wani sinadari ne na bitamin ya tsufa kuma a mafi kyawun ana ɗaukarsa a matsayin "abu mai kama da bitamin."

Wataƙila abin da ya fi shahara shi ne tasirin PQQ akan mitochondria, wanda ke samar da kuzari (ATP) da kuma daidaita metabolism na tantanin halitta. Masu bincike sun lura sosai da tasirin PPQ akan mitochondria kuma sun gano cewa PQQ na iya ƙara yawan mitochondria har ma da inganta ingancin mitochondria. Wannan muhimmin dalili ne da ya sa PPQ ke da amfani sosai. Enzymes da ke ɗauke da PQQ ana kiransu glucose dehydrogenase, wani furotin na quinoa wanda ake amfani da shi azaman firikwensin glucose.

Amfanin Pyrroloquinoline Quinone

Samun mitochondria a mafi kyawunsa yana da matuƙar mahimmanci ga rayuwa mai kyau wanda za ku iya samun fa'idodi da yawa yayin shan ppq. Ga wasu daga cikin abubuwan da suka fi muhimmanci game da fa'idodin quinone na pyrroloquinoline.

Ƙara Makamashin Tantanin Halitta

Saboda mitochondria yana samar da makamashi ga ƙwayoyin halitta, kuma PQQ yana taimaka wa mitochondria aiki yadda ya kamata, kuzari a cikin ƙwayoyin halitta yana ƙaruwa gaba ɗaya; wannan shine tsarin Pyrroloquinoline Quinone mitochondrial. Ana karkatar da kuzarin ƙwayoyin halitta mara amfani zuwa wasu sassan jiki. Idan jikinka ba shi da ƙarfi duk rana, ko kuma kana jin gajiya ko barci, to ƙaruwar ƙarfin PPQ yana da mahimmanci a gare ka. Wani bincike ya gano cewa bayan shan PQQ, mutanen da ke da rahoton matsalolin makamashi suna da ƙarancin gajiya sosai. Idan kana neman wani abu don ƙara kuzarinka, PQQ na iya taimakawa da hakan.

Hana raguwar fahimta

Tare da ci gaban kimiyya, masana kimiyya sun gano cewa abin da ke haifar da ci gaban jijiyoyi (NGF) na iya girma da murmurewa. A lokaci guda, an nuna cewa PQQ yana da tasiri mai kyau akan NGF da kuma ƙara girman jijiyoyi sau 40. NGF yana da mahimmanci don ƙirƙirar da kula da sabbin ƙwayoyin jijiyoyi, kuma yana iya dawo da ƙwayoyin jijiyoyi da suka lalace waɗanda za su iya hana aikin fahimta. Kwayoyin jijiyoyi sune ƙwayoyin da ke aika bayanai, don haka kwakwalwarmu za ta iya sadarwa tsakanin kansu da sauran sassan jiki. Inganta inganci da adadin ƙwayoyin jijiyoyi na iya inganta fahimta. Saboda haka, PQQ yana da ci gaba na ɗan lokaci.

Tallafawa lafiyar zuciya da jijiyoyin jini

Pyrroloquinoline quinine yana ba da tallafin antioxidant da mitochondrial. Bincike ya nuna cewa PQQ da CoQ10 duka suna tallafawa aikin zuciya da kuma amfani da iskar oxygen yadda ya kamata a cikin ƙwayoyin halitta. Pyrroloquinoline quinone yana hana damuwa ta oxidative ta hanyar sake farfaɗo da shi.

Pyrroloquinoline Quinone Disodium Gishiri (PQQ): Fa'idodi, Amfani, da Jagorar Tsaro

Gabatarwa
Pyrroloquinoline Quinone Disodium Gishiri (PQQ) wani nau'in PQQ ne mai narkewa cikin ruwa, mai narkewa cikin ruwa, mai haɗin redox tare da ƙaƙƙarfan kaddarorin antioxidant. Ana samunsa ta halitta a cikin adadi kaɗan a cikin abinci kamar kiwifruit, faski, da barkono kore, PQQ ana amfani da shi sosai a cikin kari na abinci don fa'idodin ƙwayoyin halitta da jijiyoyi. Sama da kashi 80% na kari na kasuwanci suna amfani da sifar gishirin disodium saboda ingantaccen kwanciyar hankali da samuwarsa.

Mahimman Sifofi

• Tsarin Sinadarai: C₁₄H₄N₂Na₂O₈ (Nauyin ƙwayoyin halitta: 374.17)
• Bayyanar: Foda mai laushi mai launin ja-launin ruwan kasa zuwa ja-lemu
• Tsabta: ≥98% (An tabbatar da HPLC)
• Narkewa: 3 g/L a cikin ruwa a 25°C
• Rayuwar Shiryayye: Yana da ƙarfi na tsawon watanni 36 idan aka adana shi a cikin kwantena da aka rufe, nesa da haske da danshi.

Fa'idodin Lafiya

1. Yana Haɓaka Makamashin Tantanin Halitta: PQQ yana kunna biogenesis na mitochondrial, yana haɓaka samar da ATP da kuzarin tantanin halitta.
2. Yana Taimakawa Aikin Fahimta: Nazarin asibiti ya nuna ingantaccen ƙwaƙwalwa, sassaucin fahimta, da saurin gudanarwa, musamman ga matasa (shekaru 20-40).
3. Tasirin Antioxidant da Neuroprotective: Yana rage tsattsauran ra'ayi, yana rage damuwa ta oxidative, kuma yana haɓaka haɗakar abubuwan da ke haifar da ci gaban jijiya (NGF).
4. Lafiyar Zuciya da Jijiyoyin Jini: Yana kare jiki daga lalacewar iskar shaka a tasoshin jini kuma yana taimakawa aikin zuciya.
5. Ƙarfin Hana Tsufa: Yana ƙara lafiyar fata ta hanyar rage lalacewar iskar oxygen da kuma inganta haɗakar collagen.

Aikace-aikace & Yawan Sha

• Nau'o'in da Aka Fi Soma Amfani da Su: Shawarar shan magani a kullum: 10-20 MG don lafiyar jiki gaba ɗaya; ana iya amfani da ƙarin allurai (har zuwa 40 MG) a ƙarƙashin kulawar likita.
  • Kapsul/Softgels: 10-20 MG (sau da yawa ana haɗa su da CoQ10 don tasirin haɗin gwiwa).
  • Foda/Ruwa: 7–20 MG a kowace hidima, ya dace da gaurayen abin sha ko abinci mai amfani.
• Sauƙin Tsarin:
  • Gishirin Disodium na PQQ: Mai narkewa cikin ruwa, ya dace da ƙwayoyin magani, allunan magani, da abubuwan sha masu laushi.
  • PQQ Acid: Mai narkewa a cikin mai, ya dace da gels masu laushi da abubuwan sha masu emuls.

Inganci & Tsaro

• Gwaji na Mutum na Uku: An tabbatar da tsarki (≥98%) da ƙarancin sinadarin ƙarfe mai nauyi (gubar ≤0.5 ppm, arsenic ≤1 ppm).
• Bayanin Tsaro: Gabaɗaya ana gane shi a matsayin amintacce (GRAS) a allurai da aka ba da shawarar. Tuntuɓi mai ba da sabis na kiwon lafiya idan kuna da juna biyu, kuna shayarwa, ko kuna shan magunguna.
• Ajiya: A adana a cikin sanyi da bushewa (2-8°C) don tabbatar da kwanciyar hankali.

Muhimman Abubuwan Da Ake Tunani

• Tushen Halitta vs. Karin Abinci: Duk da cewa akwai PQQ a cikin abinci, ƙarin abinci yana da mahimmanci don cimma allurai masu tasiri a asibiti.
• Matsayin Dokoki: An amince da shi a matsayin sabon sinadari na abinci a cikin EU da China, tare da ci gaba da bincike don faɗaɗa aikace-aikace