Sunan samfur:Lupeol Foda98%

Tushen Botanical: Mango, Acacia visco, Abronia villosa, Dandelion kofi.

CASNo:545-47-1

Launi:Fari zuwa fari-farifoda tare da halayyar wari da dandano

Musammantawa: ≥98% HPLC

GMOMatsayi: GMO Kyauta

Shiryawa: a cikin 25kgs fiber ganguna

Adana: Ajiye akwati a buɗe a wuri mai sanyi, busasshiyar wuri, Nisantar haske mai ƙarfi

Rayuwar Shelf: watanni 24 daga ranar samarwa

Ayyukan Halittu:

Lupeol (Clerodol; Monogynol B; Fagarasterol) wani aiki ne na pentacyclic triterpenoid, yana da anti-oxidant, anti-mutagenic, anti-tumor da anti-mai kumburi aiki.Lupeol yana da ƙarfiandrogen receptor(AR) mai hanawa kuma ana iya amfani dashi donciwon dajibincike, musamman prostateciwon dajiphenotype na androgen-dependent phenotype (ADPC) da phenotype resistant (CRPC) [1].

A cikin Vitro Bincike:

Lupeol shine mai hanawa na AR mai ƙarfi wanda za'a iya haɓaka azaman yuwuwar magani don maganin cutar kansar prostate ɗan adam (CaP).Lupeol (10-50 μM) jiyya na 48 h ya haifar da haɓakar haɓakar haɓakar haɓakar haɓakar haɓakar haɓakar ƙwayoyin cuta na androgen-dependent phenotype (ADPC), wato LAPC4 da LNCaP Kwayoyin, tare da IC50 na 15.9 da 17.3 μM, bi da bi.Lupeol kuma ya hana haɓakar 22Rν_1 tare da IC50 na 19.1 μM.Bugu da ƙari, Lupeol ya hana ci gaban ƙwayoyin C4-2b tare da IC50 na 25 μM.Lupeol yana da yuwuwar hana haɓakar ƙwayoyin CaP na duka ADPC da CRPC phenotypes.An san Androgens don fitar da haɓakar ƙwayoyin CaP ta hanyar kunna AR[1]

A cikin Binciken Vivo:

Lupeol magani ne mai tasiri tare da yuwuwar hana ƙwayar ƙwayar cuta ta ƙwayoyin CaP a cikin vivo.An auna jimlar matakan jini na PSA (wanda aka ɓoye ta hanyar ƙwayoyin tumor da aka dasa) a ƙarshen binciken a ranar 56. A ranar 56 bayan dasawa, an lura da matakan PSA daga 11.95-12.79 ng / mL a cikin dabbobi masu kulawa da ciwon daji na LNCaP da kuma Ciwon daji na C4-2b, bi da bi.Koyaya, takwarorinsu na Lupeol da aka yi wa magani sun nuna raguwar matakan PSA na jini daga 4.25-7.09 ng/mL.Tumor nama daga dabbobin da aka yi da Lupeol sun nuna raguwar matakan PSA idan aka kwatanta da sarrafawa[1]