Carbetocinwani maganin oxytocin ne mai aiki na dogon lokaci kuma mai ƙarfi na oxytocin receptor agonist wanda ke nuna babban aikin uterotonic duka a cikin vitro da kuma a cikin vivo. A cikin shirye-shiryen tsokoki masu santsi na mahaifa na ɗan adam da na dabba, carbetocin yana samar da matsewa mai dorewa, wanda ya dogara da kashi tare da tsawon lokacin aiki fiye da oxytocin saboda ingantaccen kwanciyar hankali na rayuwa. Nazarin magunguna yana nuna ƙarfi ga masu karɓar oxytocin yayin da yake nuna ƙarancin aiki da ke da alaƙa da vasopressin a yawan warkewa. A cikin jiki, carbetocin yana ƙara sautin mahaifa, mitar matsewa, da girman matsewa yadda ya kamata a cikin samfuran dabbobi da yawa da saitunan asibiti. Shan magani ɗaya na jijiya ko na ciki na 100 μg yana ba da tsawaita motsa jiki na mahaifa, tare da aikin halittu yana ɗaukar lokaci mai tsawo fiye da oxytocin, yana rage buƙatar maimaita allurai.CarbetocinAn yi bincike sosai kan rigakafin zubar jini bayan haihuwa bayan haihuwa da kuma haihuwa ta farji, inda yake rage yawan zubar jini da zubar jini yadda ya kamata. Kyakkyawan yanayin maganin pharmacokinetic, tsawon lokacin tasirin mahaifa, da kuma ingantaccen ingancinsa sun sanya carbetocin kayan aiki mai mahimmanci na bincike don nazarin siginar mai karɓar oxytocin, ƙanƙantar mahaifa, ilimin halittar haihuwa, da kuma kula da zubar jini bayan haihuwa.

Sunan Samfurin:Carbetocin

Wani Suna:N-(4-Mercapto-1-oxobutyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamidecyclic (1-5)-thioether acetate

Lambar CAS:37025-55-1

Bayani: 95% HPLC

Mƙashi mai kauriFtsari:C₄₅H₆₉N₁₁O₁₂S · xC₂H₄O₂

Nauyin kwayoyin halitta:988.15